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Metabolon

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Our Precision Metabolomics™ is a powerful, patented technology for assessing health and delivering biomarker discoveries, innovative diagnostic tests, and valuable data for genomics and population health initiatives.

10/29/2026

Generating molecular data is easier than ever. Turning it into meaningful biological insights is another challenge.

As multiomics research advances, the question is no longer just what we can measure, but how we can use that information to investigate the mechanisms underlying disease.

Metabolomics brings a valuable perspective by capturing the biochemical consequences of genetic, environmental and physiological influences.

And with tools like Splash & Ripple, researchers can take those insights further.

Explore how Splash & Ripple can help you move towards testable mechanistic hypotheses.
🔗https://bit.ly/4yHo8L3

10/27/2026

Science is making great progress not only in understanding human health, but also in understanding the health of our beloved furry friends. 🐶

In a recent study, researchers from Hill Pet Nutrition, MIT and Harvard University used metabolomics to investigate the relationship between nutrition, the gut microbiome and metabolic activity in dogs.

By analysing healthy dogs fed 12 different diets, researchers found that the type and amount of dietary fibre influenced gut microbial metabolism, with higher fibre intake associated with beneficial microbial metabolites, including short-chain fatty acids and polyphenols.

Interestingly, these metabolic responses varied between individual dogs, highlighting the value of studying what microbes are doing, not just which ones are present.

▶️ Watch Brian explain why this research is an example of !

🔗 Read the study: https://pubmed.ncbi.nlm.nih.gov/39714168/

What other examples of Peak Science have you come across?

10/22/2026

How reproducible are results from the Metabolon Verus™ Kit across independent laboratories?

In a multi-site ring trial, 8 independent laboratories used the same standardized workflow to analyze plasma and urine samples from a fed–fasted study.

The goal? To evaluate whether different laboratories could consistently measure the same metabolites and capture the same underlying biological changes.

The results demonstrated strong agreement across laboratories, from metabolite detection and abundance measurements to the identification of biological differences between fed and fasted states, including:

🔸 89% average metabolite overlap across laboratories.

🔸 0.91 median correlation with quantitative targeted panels using 8-point calibration curves.

📄 Want to know more? Download the full ring trial results: https://bit.ly/4seyqAM

10/22/2026

It's been a busy few days at in Montréal, thank you to everyone who has stopped by so far! 🧬

We've enjoyed discussing how metabolomics can complement genomics to better understand the biological mechanisms underlying genetic variation.

We’ve also enjoyed sharing our newest bioinformatics application, Splash & Ripple, which helps researchers connect metabolite changes to proteins and develop testable multiomic hypotheses.

📍 If you're attending , there's still time to meet our team at Booth #620. We'd love to hear about your research!

10/20/2026

You know metabolomics captures biochemical activity that reflects the combined effects of genes, proteins, disease, treatment and the environment.

But once you have that data, do you know which mechanistic hypotheses you should investigate next?

Introducing Splash & Ripple, our newest application within Metabolon’s Integrated Bioinformatics Platform, designed to help you move from metabolomic changes to testable multiomic hypotheses.

Splash & Ripple connects metabolite changes to candidate proteins using an extensive, scientist-curated database of metabolite–protein relationships.

Bringing this evidence into one interactive environment helps researchers:

🔸 Identify candidate mechanisms supported by multiple biochemical signals.
🔸 Explore the evidence behind prioritized proteins.
🔸 Develop focused hypotheses and select experiments for validation.

An optional AI-assisted interpretation module adds citation-supported hypotheses for scientific review.

Discover where Splash & Ripple can take you: https://bit.ly/4i6PLXB

10/19/2026

During COVID-19, as in other periods of physiological stress, viruses already present in the body can reactivate. But how does this reactivation relate to how ill patients become and how they recover?

To investigate, researchers followed 1,154 hospitalized patients, combining metabolomics with other molecular and immune measurements.

Metabolomics added a crucial part of the story: the biochemical changes associated with that reactivation.

Using Metabolon’s profiling, researchers identified shifts in amino acid and lipid metabolism, including patterns shared across several reactivated viruses. These findings helped researchers understand the wider biological processes accompanying infection, linking specific viral reactivations with particular health complications.

That’s why biochemical profiling matters.

Where else could it help deepen our understanding of infection and recovery?

10/14/2026

Next stop: Montréal!

Meet the team at Booth #620 during ASHG 2026 to discuss how metabolomics can help connect genetic variation with disease mechanisms.

Plus, at our presentation on Wednesday 21st, you’ll get a first look at our newest release for our bioinformatics platform: a tool that provides a clearer path from metabolite changes to testable mechanistic hypotheses.

It draws on metabolomic inputs and works backwards from your phenotype through a comprehensive database of curated metabolite–protein interactions to connect your findings with potential biological mechanisms

What could these connections reveal? Join us to find out!

“Splash & Ripple: A Case Study: Hypoxic Ischemic Encephalopathy”
🎤 Ben Molloy, Principal Scientist, Metabolon
📅 Wednesday, 21 October | 10:15–10:45 am

10/13/2026

Great first day in Basel! 🙌

Thank you to everyone who visited Metabolon’s booth at Biomarkers, CDx & Precision Medicine Europe and NextGen Omics, Tech & Data to discuss how biochemical profiling can help resolve disease biology, uncover biomarkers and understand treatment response.

Looking forward to more conversations tomorrow! Come and meet the team at Booth #33.

10/12/2026

There’s more to lipid biology than conventional cholesterol and triglyceride measurements.

Join Metabolon’s Natasa Giallourou, Associate Director of Scientific Strategy, at the LIPID MAPS Training School 2026 to explore how complex lipid profiling helps researchers resolve the biochemistry underlying health, disease and treatment response.

Through case studies from population cohorts and clinical trials, Natasa will show how lipidomics reveals genetic influences on lipid variation, distinguishes biological differences between patients and supports the assessment of drug target engagement.

🔬 Complex lipids in health, disease and therapeutic development
📅 Thursday, 15 October | 17:25 BST

Register here: https://bit.ly/4c4njV5

10/09/2026

What’s the most important unanswered question in diabetes research?

At , we put this question to Dr. Denise Faustman of Harvard Medical School and Massachusetts General Hospital.

Her answer underscores the value of looking beyond blood glucose to investigate the cellular processes underlying disease, and how metabolomics can help researchers resolve that biology.

▶️ Watch Dr. Faustman share her perspective and explain why studying metabolites matters for the next steps in diabetes research.

Address

Morrisville, NC
27560

Opening Hours

Monday	8:30am - 5pm
Tuesday	8:30am - 5pm
Wednesday	8:30am - 5pm
Thursday	8:30am - 5pm
Friday	8:30am - 5pm

Telephone

(919) 572-1711

Website

http://metabolon.com/

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