Center for Neuromodulation in Depression and Stress

Center for Neuromodulation in Depression and Stress We understand that no mood illness is the same.

At the Center for Neuromodulation in Depression and Stress, our mission is to leverage cutting-edge neuroscience for personalized treatment of mood disorders. The Center objectives are to

Spur new research on the science and treatment of affective disorders

Fully integrate state-of-the-art neuroimaging with cross sectional and longitudinal phenotypic characterization, including blood and

CSF biobanking

Use molecular neuroimaging to identify changes in stress-related neuroplasticity, neuroreceptors, inflammatory cytokines, reactive oxygen species, amyloid and tau proteins in stress and depression-related disorders

Capitalize on and strengthen efforts of the outstanding neuroscience community at Penn, including links within and across the Penn departments with stress and depression populations

Mentor junior faculty and trainees who are focusing their training on issues related to affective illness

Hello everyone! Our lab is currently recruiting adult research volunteers for an in-person study investigating the effec...
06/18/2025

Hello everyone! Our lab is currently recruiting adult research volunteers for an in-person study investigating the effects of transcranial magnetic stimulation (TMS) on bipolar depression. TMS is a non-invasive and personalized treatment that uses targeted magnetic pulses to stimulate the brain in specific areas. Study visits will take place on the University of Pennsylvania campus, and you will be compensated for your time and participation. For more information, please feel free to reach out to one of the contacts listed on the flyer or comment directly under this post. If you are interested, please fill out our screener at this link; the information that you provide, such as your medical history and demographics, is handled with strict confidentiality and adheres to all relevant data protection regulations, such as HIPAA.

Make sure to check out Dr. Sheline's new Substack: Voluntary medication supervision fails:
05/06/2025

Make sure to check out Dr. Sheline's new Substack: Voluntary medication supervision fails:

Mandatory supervision was the only time he had been stable and it needed to be reinstated

Make sure to check out Dr. Sheline's new Substack: Parent-supervised medication
04/30/2025

Make sure to check out Dr. Sheline's new Substack: Parent-supervised medication

He now also needed oversight and help managing his apartment

Make sure to check out Dr. Sheline's new Substack: Not able to manage
04/21/2025

Make sure to check out Dr. Sheline's new Substack: Not able to manage

Self care and taking care of the apartment were out of his grasp

Make sure to check out Dr. Sheline's new Substack: No Job
04/14/2025

Make sure to check out Dr. Sheline's new Substack: No Job

It felt unbearable and was destabilizing

Make sure to check out Dr. Sheline's new substack: Essential Worker!
03/24/2025

Make sure to check out Dr. Sheline's new substack: Essential Worker!

This was a source of pride

Make sure to check out Dr. Sheline's new substack: Dismemberment of Dane County Mental Health
03/12/2025

Make sure to check out Dr. Sheline's new substack: Dismemberment of Dane County Mental Health

Decline in Mental Health Services and destabilization in mental health

Make sure to check out Dr. Sheline's new substack: Origin of community based treatment:
03/03/2025

Make sure to check out Dr. Sheline's new substack: Origin of community based treatment:

from asylum to state hospital to deinstitutionalization.

Make sure to check out Dr. Sheline's new article: Alternative treatment options for seriously and chronically mentally i...
02/24/2025

Make sure to check out Dr. Sheline's new article: Alternative treatment options for seriously and chronically mentally ill patients—

Did I make the right choice?

Make sure to check out Dr. Sheline's new article: Mental-Health Disability Support Can Be Temporary or Permanent
11/20/2024

Make sure to check out Dr. Sheline's new article: Mental-Health Disability Support Can Be Temporary or Permanent

Personal Perspective: Disocvering the supports available from the university disability office gave me a flicker of hope for the first time in a long time.

📬 Dr. Sheline's latest Substack post is live! Make sure you’re subscribed so you don’t miss any future updates! 👇
11/11/2024

📬 Dr. Sheline's latest Substack post is live! Make sure you’re subscribed so you don’t miss any future updates! 👇

How is disability determined?

Address

3700 Hamilton Walk
Philadelphia, PA
19104

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