08/09/2026
Over the years I’ve been given quite an impressive variation of anti anxiety and antidepressant medications. None of them ever really helped.
It felt like a revolving door. I’d sit opposite my GP and try to explain what was happening, exhausted all the time but somehow unable to sleep, my head full of a hundred different thoughts from the moment I woke up, always worrying and overthinking about everything.
I’d be told it was anxiety and depression and leave with yet another prescription.
The medication never really helped, and I didn’t know why.
I told myself it was my fault. That I was somehow failing, and that I was wasting everyone’s time. So I’d leave it for months, sometimes years, before going back and asking for help again.
Then perimenopause came along and turned the volume up on all of it. My anxiety increased, my confidence plummeted, my memory got worse, and my emotional regulation, my imposter syndrome, my rejection sensitivity, all felt magnified.
Hormones affect the brain, and research is increasingly showing that hormonal changes can influence ADHD symptoms in women, with oestrogen in particular playing an important role in the brain’s dopamine system, including dopamine production (Kooij et al., 2025).
Perimenopause can mean years of fluctuating and falling hormones. For women with ADHD, these hormonal changes can have a significant impact on the things that already take more effort, like focus, motivation, memory, organisation and getting things started or finished.
I thought I just needed to try harder. What I really needed was someone to understand the bigger picture.
If clinicians don’t understand how ADHD can present in women, or how hormonal changes can affect a neurodivergent brain, they may continue treating the symptoms they can see without recognising what else could be contributing to them.
How many women are repeatedly being treated for anxiety and depression, without anyone asking what else might be going on?
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