05/09/2026
The popular framework
Calories for weight, macros for looks, micros for feel - captures partial truths but oversimplifies deeply interconnected biology.
Macronutrients do not act independently; their interac- tions shape appetite, thermogenesis, and adiposity in ways that cannot be predicted from single nutrients studies.
WALI 2021
SIMPSON 2026
Individual genotype and gut microbiota further alter responses to specific macronutrient intakes, explaining why identical diets produce different outcomes across individuals.
San-Cristóbal
2020
Martínez
2014
This is why you hire a professional coach: to break down the literature. 💯 📈