02/14/2025
Evaluation of inhaling five essential oils—Jasmine sambac, lemon verbena, balsam fir, Magnolia denudate (lily tree), Rosa rugosa (beach rose)—in a serotonin depleted insomnia model found that the oils reduced the time taken to fall asleep and improved total sleep time. Each of the oils increased the expression of 5HT1A and GABAARα1 proteins, associated with relaxation and sleep regulation, with lemon verbena and balsam fir (an odd chemotype with 60.3% linalool) being the most effective. The EOs also reduced pro-inflammatory cytokines (IL-6, IL-1β, TNF-α), suggesting they may help with stress-induced sleep disturbances.
Thanks Dr. Scott Johnson for this important post!
https://pubmed.ncbi.nlm.nih.gov/39848678/